Nyckelord
acute
Chronic
Cardiovascular
Heart failure
Abstract
Background: Heart failure is the ultimate effect of
all cardiovascular disorders with a rapid increase in
its prevalence. The risk of sudden death is high in
heart failure and has been attributed to progressive
pump failure and arrhythmias especially ventricular
arrhythmia.
Objectives: This study aims to determine the
arrhythmia burden in heart failure patients
Methodology: Ninety adults with heart failure were
assessed. A 24-hr Holter Electrocardiographic
monitoring was done using a 12 - channel Edan®
Holter recorder, trans-thoracic echocardiography and
rest ECG was performed on all subjects. Continuous
variables were compared by the student’s t- test while
categorical parameters were compared with the chi
square test or two tailed Fisher’s exact test as
appropriate. Pearson’s correlation coefficient was
used to assess the relationship between
echocardiographic parameters against the number of
arrhythmia/hours on Holter ECG.
Results: The mean age of the subjects was
49.8±14.4years with a female preponderance of
1.4:1. Arrhythmias such as isolated ventricular ectopic
(100%), isolated atrial ectopics (91.1%) non
sustained ventricular tachycardia (16.7%) and atrial
fibrillation (20%) were noted on Holter ECG. There
was a significant positive correlation between the left
ventricular internal wall diameters in diastole (LVIDd)
and the number of VE/hour (p = <0.001) with a
negative correlation between the ejection fraction and
the number of VE/hour (p = 0.023).
Conclusion: The frequency of arrhythmias is high
in heart failure patients. Left ventricular systolic
dysfunction and chamber size were major
determinants of arrhythmias and could be used in
identifying high-risk patients in a bid to initiate
preventive measures if necessary.
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