Resumo
Aims and objectives: The aim of this retrospective study was to determine the pattern of benign soft tissue tumours in a tertiary hospital based histopathology service in South-western Nigeria.
Materials and method: The records of all benign soft tissue tumours diagnosed in the Department of Pathology, University College Hospital, Ibadan, between January 1970 and December 2002 were retrieved, and reclassified using the 2002 World Health Organization classification of soft tissue tumours. The sites of lesions were coded into five categories: upper extremity, lower extremity, head and neck, trunk and abdomen. Clinical information obtained included age, gender, histopathological diagnosis, recurrence and presence of multiple lesions. All cases where any of this information,was not available were excluded from the study.
Results: Two thousand two hundred and thirteen (2213) cases fulfilled the inclusion criteria out of 2801 cases retrieved from the records of the department. They comprised adipocytic tumours (accounting for 55.5%), vascular (24.5%), fibroblastic/myofibroblastic (9.4%), fibrohistiocytic (8%), smooth muscle (0.9%), perivascular/pericytic (1.2%), chondro-osseous (0.1%) and tumours of uncertain differentiation (0.4%). Overall male: female ratio was 1:1. The age range was from 5months to 83 years, with peak age group of 30-39 years in males and 20-29 years in females.
Conclusion: This study shows a similar pattern of benign soft tissue tumours in our series to what obtains in other parts of the world, although our patients tended to be younger, a reflection of the population structure of our country. However, in contrast to Caucasian series, deep fibromatosis was observed to be far more common than superficial fibromatosis. Also giant cell tumour of tendon sheath has a slight male predominance in contrast to overwhelming female predominance in other series.
Keywords: Benign, soft tissue, black Africa
Résumé
Le but de cette étude rétrospective était de déterminer la fréquence des tumeurs bénignes des tissues doux dans un centre tertiaire base sur le service histopathologique au sud-ouest du Nigeria. Les registres de tous les tumeurs bénignes des tissues doux diagnostiqués au département de pathologie, Centre Universitaire Hospitalier, Ibadan, Nigeria entre janvier 1970 à Décembre 2002 étaient retires, reclassés utilisant la classification de l’OMS des tumeurs des tissues doux. Les sites des lésions étaient codés en cinq catégories : extrémité supérieur, extrémité inferieure, la tête et le cou, le tronc et l’abdomen. Les informations cliniques obtenues inclues: l’âge, le genre, le diagnostic histopathologique, la récurrence et la présence des multiple lésions. Tous les cas ou aucune information a l exception de la récurrence et des multiple lésions, étaient exclus de cette étude. Deux mille deux cent trente un (2231) cas obéissaient aux critères inclusion des 2801 cas retirés des registres du département. Ils étaient constitués de tumeurs adipocytiques (estimant à 55.5%), vasculaire (24.5%), fibroblastique/myofibroblastique (9.4%), fibrohistiocytique (8%), muscle lisse (0.9%), perivasculaire/pericytique (1.2%), chondro-osseuse (0.1%) et tumeurs à différentiation incertaines (0.4%). La proportion totale male: femelle était de 1:1. La variation d’âge était de 5mois à 83 ans, avec un sommet d’âge entre 30-39 ans chez les hommes et 20-29 ans chez les femmes. Cette étude montre une fréquence similaire des tumeurs bénignes des tissues doux dans cet environnement comparé aux résultats d’autres parties du monde, bien que nos patients sont plus jeune, une réflexion de la distribution de la population de notre pays. Cependant chez les européens, la fibromatose profonde était observé plus commun que celle superficielle.
Correspondence: Dr. Gabriel Ogun, Department of Pathology, College of Medicine, University of Ibadan, Ibadan, Nigeria. E-mail: olabiyiogun@yahoo.co gogun@comui.edu.ng
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