الملخص
Background: Diffuse pulmonary ossification is a relatively rare disease characterized by the presence of small bone fragments within the lung tissue. Patients are generally asymptomatic, but when symptomatic, diffuse pulmonary ossification is usually associated with other pulmonary diseases such as interstitial pneumonia, fibrosis, or bronchiectasis.
Material and method: We report the case of an asymptomatic 45- year old female Nigerian woman seen at autopsy.
Results: Histology surprisingly revealed lymphocytic thyroiditis, in addition to confirming dendriform pulmonary ossification and background focal interstitial pulmonary fibrosis.
Conclusion: The association of Diffuse pulmonary Ossification with lymphocytic thyroiditis has not been previously reported.
Keywords: Diffuse pulmonary ossification, lymphocytic thyroiditis, African female
Résumé
Diffuser l’ossification pulmonaire est une maladie relativement rare qui se caractérise par la présence de petits fragments d’os dans le tissu pulmonaire. Les patients sont généralement asymptomatiques, mais quand ils sont symptomatiques, l’ossification pulmonaire est généralement associée à d’autres maladies pulmonaires telles que la pneumonie interstitielle, la fibrose ou une bronchectasie. Nous rapportons le cas d’un asymptomatique de 45 ans, une vieille femme Nigerian vue lors de l’autopsie et chez qui l’histologie a révélé étonnement une thyroïdite lymphocytaire, en plus pour confirmer l’ossification « dendriforme » pulmonaire et à l’arrière-plan focal une fibrose pulmonaire interstitielle. L’association de la diffusion de l’ossification pulmonaire avec une thyroïdite lymphocytaire n’a pas été rapportée précédemment.
Correspondence: J.Olufemi Ogunbiyi, Department of Pathology, University College Hospital, Ibadan. E-mailfogunbiyi@comui.edu.ng, f_ogunbiyi@yahoo.com
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